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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f937ebdf79ae2f899de5d5b82f49a7815fef8f752a8381c74c0f4d5d2b4893' 
  AND token = 'b7dDXh6v+Xzhkf3oKcf8Z/F6ce+yxxfBR4UzYvFv2oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}