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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946456d11ee103485cfaa0b59fd6e3ef01008956d8e089967e9999e2f7521a07' 
  AND token = 'ZZMVJEpBwugYrpOmH6kLRV050uNonTMwoix/+lM/xmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}