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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2663af480cb25d07502d3ae76f64818d9bf8e2ce7c543ed0506ce40dabd77060' 
  AND token = 'F0cuaFO8qVlX0f1GkSLJ74pa9wmMbsnemNZsrY2l6Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}