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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335323694422e0c6e9ffe2b7ef52948d48798c92b9e6064f4a2ca9c07fdc71e4' 
  AND token = '/fv7Rdxtq3VyOFmDuyIsFsqm/QHWgnlXYjnjt8gev4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}