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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491481303cba454130429b02af29531569421417b82b0856d2acecdfe1ce12c3' 
  AND token = 'ZAblql14zoNTgM2nV4Gnba8OcquuStMm8BmhcHRLFc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}