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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8614c1bcd6fa5732057f194e05481c983363af85d0cc54b4bfac86e50d3086e0' 
  AND token = 'nwSU15mIMYh7b1ooRcSS6tO00z8bK5Z0zmWKeGKVe9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}