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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28da8fd51f8006d433ffc90fa059ab9ccb9014e29edb573a05b187b3fc3924c2' 
  AND token = '7Aj2yngYFDaL2VIFtT2lt/BIiuJZ3RE5A1agHKC2Gck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}