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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd541184b90f9e85d37a7e3f08ac181c9ae3813b3211d01f775be25ef155db807' 
  AND token = 'vGPxhVCW0tryYYPGv4fXE8JSDB+tcj24Mhij6doN3Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}