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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc7c402930fa1e4e2e2c590bd4f756c45a5a3e92c0d827d39da004173d178c5' 
  AND token = 'UsBkb0XwV7py+fqrqdEqBD/ZSuh2P9+x56ag5FfNINs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}