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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47653ffb83e72cdac8ae3e342924d982b5758956a42703d44164794820caccf8' 
  AND token = 'gMy2iJW2kBbNeJhnTmsvqe9GTYLhEO+rrGOm5XGOZR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}