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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5538bdc831a3bf5480889be81a2c481e39a9891a93b64e8c3565e2124d39373' 
  AND token = 'BqD3fWVAJLG+k5dHWBNxipQJqeje0lkCGsE2ta5xPwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}