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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fb8e8fa308db4092eed3146ead85c5778d2e7a23f76243c0d9b388ed402332' 
  AND token = 'eDdYm0e0cCnmPKqYD1juf7zKZ+zcPNDthojgVkOwxw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}