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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca462b4a9d4248fa844d7b7083ac62d4b38d34c6dd387fed01c0631746190aff' 
  AND token = '2J16UVJLYIifT65iJL/EZE5ty275ZBXPs3GgdDmL2/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}