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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe38ba4a640c40b3f334f5197a24c14be1f3919c3f261c134d4e6aa956fc2a6d' 
  AND token = 'BqAYG1ODhsw57r4kSd5R1lCpC2lUEtwsVBL7CU4C8hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}