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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c47c99d9acd33913013a054c3f913653a482c6789e339ca786ba4ede1acb27f' 
  AND token = 'A3zplmybcqAkNkW9+FTvy4NR3RDl95gL1MNxism37ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}