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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79670b4231650439099fdf355dc6450b8a812ad7bc129b01694f3c7c24550ac9' 
  AND token = 'jPfiXEKrOZ8WDrfePx6OoFim+Ei9ewksckFe5jsk9Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}