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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79667aaecc6285dd885fd5f05aaace6de945f16d9e3330c3f77cb5b279f42323' 
  AND token = 'YJjBM+wdsf/rtpRT3oy/Twz/JTy0yW/ZptEcLB9qA3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}