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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c22e3ea63c795015e415125dd619c9a309f7ecff6b1f06b9820a03108b4a63e' 
  AND token = 'TT45uY/67MagYFqUNtFu24O3mkvXe9P4KzfA+qGvQ9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}