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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4d382bfd0e9ef3329f19a836577ca34ff4cf8951b2c0ed669baeabb30f6c3d' 
  AND token = '++muLT7AjCdCnup+aUwU6w499zO3HMtZyRJg+erYaUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}