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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65953e45b5b5937fcb3f0b94d804411a426dac2ce6303e713600bfd8648c3751' 
  AND token = 'eI3zAvnGtwI5IgrPNQhlJOzbTbQ1GZJezxGl5nIdI8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}