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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '715f9d601d9e59155338065a5aef9f332683f6b57a57d5030dc6b5734830d001' 
  AND token = 'Pk+ucyyPYjAZLExgOTT5K3e15LPQ0mLcHlk0VYl+bT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}