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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d380ce3e60a0c37dfe39538d2d9cffbc684e2165c1089da8a1c760a33d5b780' 
  AND token = '7M/wun0s/PqyrDGcB0m61CSdI24BEnxO7XJftSsoIfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}