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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e3fbab8ee95c69ae01afdafaa2a5c540450e3c26f7a5d9ba5e218fb5e7dc04' 
  AND token = 'D6KWLn/OXBWRCXvBNFo5g+VHaH+saF0Jc+ZMsu5ygPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}