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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b19d97e5cb046cf0451074e4ef3da308a35180cea00ef3851e8c48686de96d3b' 
  AND token = 'HW1yiSm/KtW5f1xjO1rRSdavmyBnWkDb9z6Fnl1bRqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}