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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d3eb84fa5d97478cf37d23a757b257a52115bbaacb032c16117ac43feb68f0' 
  AND token = 'tzy9R1YhWc39vKBjkhHym5HY68My2UnjWUMm+RIGtlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}