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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec8bb39fc1829ed134cd2eb42a7d66b1168891a0a5aa430eccf5738d9f82b14' 
  AND token = 'vz7LJ3+f/rYqjmVbpdBVBEm01I59ES11FWCHiGfcMs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}