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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afadf3dc2cb2be21dc35fdd8f3df88fd62b1c8f3e7f1a5f48f6814138862a918' 
  AND token = 'WAf19oXSiqNC/2wRzJUakcHyZp2t8q8G8EZW9fadqqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}