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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2416a88cbc3c7a39ce2069c31a33a5b01dac7debe9eb7dc9124d8f694dd4c1f' 
  AND token = '28VaHMaET23LJDYHEiYcf8bdUSV8YV2+mA8IOWTefLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}