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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12746daa67d9eb4c2dfdeb0e8b8820f1572c2d1a06bb08e0f269910646f214ef' 
  AND token = 'OyBVKpCyxkTGZ+5M5UvmqkIMj3MuMXhavx+N019BzTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}