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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4785e5eb746bab441886ab27f431b834cba6ba9a3f8d48ac27f8f4f11cbbb0c8' 
  AND token = 'Yd0Msgx7WxFp0VZ/Q86h/+YRI8NsKJBCD+dxXYTAogg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}