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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '838ffa92cd82a92ecdb3491074baf4ce76c17dcd7b44797bcde5057b6606e216' 
  AND token = 'pyvraokjdWfq72MUh1VmQNROgCWbk9wg0HIjOc6NNc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}