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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06651af2feea0348480a3948e623b44e5c7b76cb0322823987d040649a4ffd00' 
  AND token = 'j1TYbopVf5N7i6VJVbrJzTHGroU8K7IGmhveK85flGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}