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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9714b372d2e5ceed304337d9fa35386233383c2b2c07c116225f2874579354ad' 
  AND token = 'QWElYQvliuPssVcu4Q2G7t8ffOMASwdfO4XJI2G3Ekc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}