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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f867892731aa780488abf086625c8807dccdcfe6b5b01b8137bd5872b2a9484' 
  AND token = 'a0S9ZAKMrkBtkh2yB01SyKDv3FPLXh/gdQTg84WWFg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}