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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d30d699fc995ba089808218c1f7ad81a641002311d4b92e7fd630975d5a327' 
  AND token = 'PVJaNQW0utKsp2RUrE4cFm0RJaj7H4dcTDXZ2kiBn1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}