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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9878d1a54060b78da786a8b7d0a3f0abe7aa61b27c101257795822f5f0a12c88' 
  AND token = '3cxEKN/xNF7braPomFogJx7Q/QUVSwYjwujCEmDtr8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}