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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fbe24581e1923d4c042effcdc18fc372458080591b2b59f5a97ad4188cb7be7' 
  AND token = '6KOK9B1RSXq73JaX03mdyMJFMd+wH2ptI82hwT/t9dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}