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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca222b41eca0b08d7e2862ae72a526f4011bff6f24f1c25b2d0feb93834fb17' 
  AND token = 'VFV0GLL1tsEI08dkvtaKFq1Sm7lPlIMBbdSQlholcVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}