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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47a36ef1fd42fbf2cdabd3cc887ed4ee78a45eac76417834ae77101593d713e6' 
  AND token = 'tjazolOAPm1WNXrUxl4xO6XIaCvj+LKtmJ2rGuXbCP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}