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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d41b082f399ada5de7023e63926e4df0543ec254c3695cad691979d4638c681' 
  AND token = 'uLv4yeH6/gYxQpikX9UI6ReWXpTLZyUq/ZBEBsR8cD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}