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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d68c7d65a5b6143039eeedbbf1487e3b82ef1112a14580d3882c4545a105bdf' 
  AND token = 'xi4Cwj1L5KdO23KnUCIFWSq3T8ksf1dyPjOJSzpBlxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}