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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6bb52987aee55711ac65f61a545dcbe0d61d0411b1a52be04a60a68d181262d' 
  AND token = 'B5kQVcPiPn9OhT0I5FadUwjM6SWkPPAF0CwCae2Rp7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}