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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5514a1d82e55d89047ad6772448af7f39bf4218ef7eefc90a9b14095c303f99' 
  AND token = '/18fIOsb8efPf2MmzSTjN5mPzUiTRu3XK7wn5KOh6Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}