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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1107c10c604e4ca210f9aa5d7cd24952a60c0d0062ecec2613ece9305451096' 
  AND token = 'o/3YkJJzITULBvyPjO1qClEJe5iL1DGnkmZPHz3mW4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}