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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb060a612b9b7754568c0b4c7600a1019423cd13837e9d31f2f5b500d490a1c9' 
  AND token = 'CX0ptoGNq6zvjnR/MYEFjk13sXo8AYXUam1VIhTg9dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}