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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed89a3e4249ffb802f88904d7b9eb5c69b25d54f452080a889e9d83712b0864f' 
  AND token = 'jWavUtukYRb73AmzYNhz5VzlAPUKtzcbktAJoKjhFYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}