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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae11b0f135889b4e2378d7d793e6b06b3f7987cb4b0157d46e5272d74dc21db' 
  AND token = 'SqSuGh7fpFvEfo1Ps2Swr1J8nnKNdlQYnult3PTIAiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}