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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f210dc0e20d21c7100b8ddd8a7033a0d4e9ff4157f7d031db49ed52928f276' 
  AND token = 'IvkuAG7xPMlafQQ72j+BgH2JOvwRQ9qzxsiCyR6ihYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}