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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e27e327706122b65113348e213d24ac031a3518ac488dc68e2a6370abbab64a' 
  AND token = 'pB4sQWC42zpqJQYQ88yTgWwm01HL+TRMNkD5tS5Trsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}