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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5b21ad20b5816fe3ae0b218366ef898a30131d56cbcf3be70f7ead67af7b00' 
  AND token = 'y2G1S7vRmpqCSn6U5nhB3Muph7JVif+OIL2ovgqc8Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}